crispr

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Base editing with reduced DNA nicking allows for the simultaneous editing of over 10,000 loci (13,000) in human cells. Performing this feat in the human genome will require the modification of 4438 Amber codons. They have shown that gene editors …

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CRISPR-Cas9 gene-editing system has made pluripotent stem cells that are functionally “invisible” to the immune system which will prevent rejection of stem cell transplants. Universal stem cells can be produced that will work for everyone and there will not be …

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Salk Institute researchers have used CRISPR/Cas9 therapy to suppress aging, enhance health and extend life span in mice. Above – This image shows two mice of the same age with progeria. The larger and healthier mouse on the left received …

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George Church describes going beyond cutting DNA to precise editing. 1. Phage Integrases (Protein and DNA) 2. TAL Deaminases (custom Protein) 3. Chemical Targeting (custom polymer) 4. lambda (λ)-red recombinase (Custom DNA) Beyond editing to writing large genomes DNA-based target …

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Kheiron Biotech using clones thoroughbred horses and announced in 2017 that they would use CRISPR gene editing to create super horses. They plan to perform myostatin inhibition to boost the muscles in horses. They will develop horses with more muscle …

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There is about 70% support among Americans to use human gene editing to cure or correct diseases. The support among people in China for using human gene editing to cure disease was similar in a recent poll. The US support …

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The chinese geneticist who has gene edited twin baby girls is reportedly missing. He Jianku caused a controversy for being the first case that we publicly know of for the genetic modification of the human germline. The Shenzhen University where …

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I have covered the technical aspects of the gene editing of the human twin babies, but I have not had a focused look at only the ethics, compassion and noble intentions involved in this situation. I He primary motivatation for …

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The question and answer interview of He Jianku conference presentation has the most interesting parts of this debate about human gene editing of embryos. The interview starts at about 1 hour and 28 minutes of the record. The formal presentation …

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During his presentation of the CRISPR gene editing of human embryos, the Chinese scientist said there is another woman currently pregnant with a gene edited embryo. He Jiankui is an associate professor at the Southern University of Science and Technology …